Designed to overcome the exhaustive search for suitable protein crystallization conditions, the Wizard Classic suite of sparse matrix method screens is biased towards and selected from well-established crystallization conditions for macromolecules. Different concentrations, components and pH values are used to narrow down favorable conditions for a particular protein. Structural genomics centers worldwide use the Wizard Classic suite as initial crystallization conditions for proteins, peptides and protein complexes.
Wizard Classic 3 and Wizard Classic 4 were developed from proven, successful solutions from which others have grown crystals. In the case of Wizard Classic 4, the screen was developed from successful hits that EmeraldBio obtained in-house from SSGCID proteins and these were cross referenced to screens 1,2 and 3 to ensure there was no overlap or close similarity in conditions.
96 Formulations, 10 mL volumes.